The HibernX Series

Automated Stores for Frozen Plasma

-65°C to -18°C

Blood establishments manufacture tens to hundreds of thousands of units of the recovered plasma and plasma from plasmapheresis procedures.
High costs of virus inactivation procedures make quarantine the best safeguard method for stored plasma. Due to logistic challenges blood establishments, specially in centralised environment, are forced to store substantial amounts of this frozen component over a significant period of time.

Currently the storage process involves lengthy and tedious operations. The storage of blood components is the last element in the chain of blood derivatives production which has not yet been successfully automated.
The new LiCONiC HibernX now revolutionizes the plasma production process by providing complete automation and full traceability during storage.

HibernX Series Overview

HibernX RBB

HibernX operates by storing individual units on reusable trays or in disposable carton boxes, which fit on uniquely designed compact shelves. The shelves within the HibernX are accessed by a XYZ-coordinate robotic handling shuttle system from/to a buffer carousel to speed up the loading and unloading process. The fully featured system control software manages all storage processes, monitors temperature and other important climate conditions within the device. The interface of the control software allows simple integration with existing or commonly used LIMS system.
Temperature uniformity and stability is ensured by an energy efficient redundant refrigeration system that contains a CO2 back up system to safeguard the environment for the frozen plasma.

HibernX was developed due the demand for long/mid term plasma storage and convenient access to individual FFP units. It is the world’s first fully automated -30°C plasma storage solution. HibernX perfectly suites the requirements of blood establishments of different types: blood donation centers, plasma collection centers and hospital blood banks.
Within minutes plasma units can be retrieved based on chosen criteria, such as: donation id, quarantine status, blood group, donation date, etc. Additionally quarantine and released material can be kept in separate partitions of the storage space.

HibernX RBB cross section

Benefits

Simplified workflow
Convenient storage and retrieval from >0°C environment
High Throughput Single Unit and Batch Access
Highest storage density
Best energy performance
Unrivalled temperature uniformity and stability
Intuitive system operation
Seamless LIMS integration
Unique no defrost cycle design

Capacities

The system’s flexibility allows a storage layout to fit the exact number of plasma units needed by the specific application and space available at the institution. Capacities may range from 10,000 units to over 200 000, assuming plasma bag sizes of 300 ml. HibernX can also be used for the storage of plasmapheresis units of 600 to 800 ml, as well as pediatric doses of 100 ml or any combination of the types.

HibernX		RBB186k0-DF	RBB242k0-DF	RBB607k5-DF
Bag Volume	Dimensions	Samples	Samples	Samples
300ml	250x135x30mm	32‘032	42‘000	105‘300

Storage Conditions

LiCONiC‘s unique chest freezer design naturally creates two important benefits: Two climate zones, one for active components at -30°C another for passive elements at -20°C and stable horizontal temperature layers in storage area.

HibernX – Regional Temperatures
Region	Setpoint
USA: AABB temperature standard for F	-18°C
USA: Plasma for further manufacture into critical medicines	-20°C
EU: most of the countries	-30°C
Russia	-35°C
Some Middle East Countries	-40°C
USA: long term storage	-65°C

Space Efficiency

The HibernX Series Automated Store for Frozen Plasma make best use of given room constraints by built to space modular design. System size and layout tailored to needs and workflow requirements.

HibernX – RBB Dimensions examples
Type	Length	Width	Height
RBB186k0-DF	9360 mm	9075 mm	3500 mm
RBB242k0-DF	10245 mm	7605 mm	5500 mm
RBB607k5-DF	12000 mm	11115 mm	7000 mm

Packages, Options and Accessories

Graphical job creation for storage and retrieval of plasma units

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Easy search of units by donation ID, quarantine status, blood group, donation date

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Complete audit trail

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Automatic inventory defragmentation

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Automatic Data Backup

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Integration to LIMS Database

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Remote Support

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Mobile Device Control

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User Access Security

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Intuitive Software

Module for Storage of Archival Samples

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RFID-Integration

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Internal Vision System

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Remote Monitoring

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Tablet Interface

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External Interface Station

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The HibernX RBB Line

HibernX RBB